基于化学治疗耐药机制探究的乳腺癌科学研究进展与 卫生经济学研究并以赤峰市肿瘤医院为例进行讨论
摘要
在分子细胞学上以抑制肿瘤细胞的有丝分裂为主。但是化学治疗后也常常伴有抗化疗药物的耐药机制的发生,并且
部分恶性患者生存率较低。我们尝试分析了部分化疗药物的作用机制通过科学实验对耐药机制进行探索,并进行分
析。通过药物价格与卫生经济学原则进行回报率等的讨论。
关键词
参考
[1]Hassan, M. S. U., et al. “Chemotherapy for breast
cancer.” Oncology reports 24.5 (2010): 1121-1131.
[2]Anampa, J., Makower, D., & Sparano, J. A. (2015).
Progress in adjuvant chemotherapy for breast cancer: an
overview. BMC medicine, 13(1), 1-13.
[3]Fisher, B., Redmond, C., Brown, A., Wolmark, N.,
Wittliff, J., Fisher, E. R., ... & Shibata, H. (1981). Treatment of
primary breast cancer with chemotherapy and tamoxifen. New
England Journal of Medicine, 305(1), 1-6.
[4]O'Shaughnessy, Joyce. “Extending survival with
chemotherapy in metastatic breast cancer.” The oncologist
10.S3 (2005): 20-29.
[5]Feldman, L. D., Hortobagyi, G. N., Buzdar, A. U.,
Ames, F. C., & Blumenschein, G. R. (1986). Pathological
assessment of response to induction chemotherapy in breast
cancer. Cancer Research, 46(5), 2578-2581.
[6]Li, X., Lewis, M. T., Huang, J., Gutierrez, C., Osborne,
C. K., Wu, M. F., ... & Chang, J. C. (2008). Intrinsic resistance
of tumorigenic breast cancer cells to chemotherapy. Journal of
the National Cancer Institute, 100(9), 672-679.
[7]Fisher, Bryant, et al. “Effect of preoperative
chemotherapy on the outcome of women with operable breast
cancer.” Journal of clinical oncology 16.8 (1998): 2672-2685.
[8]Schwartz, Anna L., et al. “Exercise reduces daily
fatigue in women with breast cancer receiving chemotherapy.”
Medicine & Science in Sports & Exercise 33.5 (2001): 718-
723.
[9]Rouzier, R., Perou, C. M., Symmans, W. F., Ibrahim, N.,
Cristofanilli, M., Anderson, K., ... & Pusztai, L. (2005). Breast
cancer molecular subtypes respond differently to preoperative
chemotherapy. Clinical cancer research, 11(16), 5678-5685.
[10]Harbeck, N., Penault-Llorca, F., Cortes, J., Gnant, M.,
Houssami, N., Poortmans, P., ... & Cardoso, F. (2019). Breast
cancer. Nature reviews Disease primers, 5(1), 1-31.
[11]Arribas, J., Baselga, J., Pedersen, K., & Parra-Palau,
J. L. (2011). p95HER2 and breast cancer. Cancer research,
71(5), 1515-1519.
[12]Key T J, Verkasalo P K, Banks E. Epidemiology of
breast cancer[J]. The lancet oncology, 2001, 2(3): 133-140.
[13]Elmore, J. G., Armstrong, K., Lehman, C. D., &
Fletcher, S. W. (2005). Screening for breast cancer. Jama,
293(10), 1245-1256.
[14]Scully, Olivia Jane, et al. “Breast cancer metastasis.”
Cancer genomics & proteomics 9.5 (2012): 311-320.
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