早期肺癌死亡率相关的因素:系统评价
摘要
期肺癌死亡率反映了局部治疗(手术或放疗)的影响(局部形式),以及转移性疾病的演变、合并症和医疗保健系统
的可及性。早期肺癌死亡率的定义并不一致;阈值范围为诊断后 1至 12个月。这项系统评价旨在识别和分析与早期
肺癌死亡率显着相关的因素。年龄、男性、非腺癌组织学、诊断时的晚期和 ECOG表现状态是早期肺癌死亡率的主
要临床因素。尽管对吸烟者身份的定义不一,但主动 /戒烟似乎也有利于早期死亡率。对于局部晚期疾病治疗的放化
疗,早期死亡率随肿瘤体积而增加。研究显示社会经济特征(农村和社会剥夺指数)产生了相互矛盾的结果,部分
原因是其研究定义的不同。然而,社会经济阶层较低的患者早期肺癌死亡率明显更高。需要前瞻性、观察性、一般
人群的研究来更好地评估早期肺癌死亡率。关于收集与患者、疾病或医疗保健系统相关的感兴趣因素的国际共识将
有助于各国之间的比较。
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PDF参考
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