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利用无创肝脏瞬时弹性成像评估 HP 感染与 NAFLD 的关系

杨雪 芳*, 李 国荣, 刘 骞, 杨 镇英, 和 重祥

摘要

目的:本研究旨在利用无创肝脏瞬时弹性成像探讨幽门螺杆菌(HP)感染与非酒精性脂肪性肝病 (NAFLD) 患者
发生脂肪变性严重程度的关系。方法:本研究纳入 2023-03-01 至 2024-12-31 日我院行无创肝脏瞬时弹性成像(TE)的
NAFLD 患者 124 例,收集碳 13 呼气试验结果及临床和生化资料,将 NAFLD 患者按脂肪衰减程度(CAP)值分为轻度脂
肪变性组和中重度脂肪变性组,分析 HP 感染与患者 CAP 的关系。结果:中重度组 HP 阳性率更高,差异具有统计学意义(P
< 0.05),中重度组空腹血糖、尿酸、HGB、GGT 和 WBC 水平较高,轻度组 PGII 较高,差异有统计学意义(P < 0.05),
使用 Logistic 回归分析进行单因素分析 HP 阳性是中重度脂肪肝的危险因素(P < 0.05),调整年龄、空腹血糖、尿酸、
GGT、WBC、HGB 和 PGII 后 HP 阳性仍然是中重度脂肪肝的危险因素(P < 0.05),且 OR 值较单因素分析上升。结论:
利用无创肝脏瞬时弹性成像分析,中重度肝脂肪变性组患者 HP 阳性率较高,且 HP 感染是中重度脂肪变性的独立危险因素。

关键词

非酒精性脂肪性肝病;HP;肝脏瞬时弹性成像;危险因素

全文:

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参考

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