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运动锻炼对血管内皮细胞影响的系统分析

刘 国纯

摘要

本研究运动文献资料、数理统计等方法,研究运动锻炼在心脑血管疾病中起到重要作用的血管内皮结构的内皮细胞的影响。分析血管内皮在心血管疾病机制中的影响,内皮祖细胞对于血管内皮的作用,运动锻炼对于血管内皮尤其是对于内皮祖细胞的影响机制。为运动锻炼在高血压疾病康复中的运动提高较好的理论建议,为相关研究的提供一般性理论参考。

关键词

运动锻炼;内皮细胞;内皮祖细胞;机制;分析

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参考

[1]Kiseleva RY, Glassman PM, Greineder CF, Hood ED, Shuvaev VV,Muzykantov VR. Targeting therapeutics to endothelium: Are we there yet[J].Drug Deliv Transl Res,2018,8(4):883-902. [2]Persson PB. The multiple functions of the endothelium: More than just wallpaper[J].Acta Physiol,2015(4)213:747-9. [3]Rajendran P, Rengarajan T, Thangavel J, Nishigaki Y, Sakthisekaran D, Sethi G, et al. The vascular endothelium and human diseases[J].Int J Biol Sci,2013(10):1057-69. [4]Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis[J].Science,1997(275):964-967. [5]Rumpold H, Wolf D, Koeck R, Gunsilius E. Endothelial progenitor cells: A source for therapeutic vasculogenesis? [J].J Cell Mol Med,2004(8):509-518. [6]Tepper OM, Capla JM, Galiano RD, et al. Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow-derived cells[J].Blood,2005(105):1068-1077. Crosby JR, Kaminski WE, Schatteman G, et al. Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation[J].Circ Res,2000(87):728-730. [8]Castelli WP. Epidemiology of coronary heart disease: the Framingham study[J].Am J Med,1984(76):4-12. [9]Paffenbarger RS, Hyde RT, Wing AL, Lee IM, Jung DL, Kampert JB. The association of changes in physicalactivity level and other lifestyle characteristics with mortality among men[J].N Engl J Med,1993(328):538-545. [10]Higashi Y, Noma K, Yoshizumi M, Kihara Y. Oxidative stress and endothelial function in cardiovascular diseases[J].Circ J,2009(73):411-418. [11]Higashi Y, Sasaki S, Nakagawa K, Matsuura H, Oshima T, Chayama K. Endothelial function and oxidative stress in renovascular hypertension[J].N Engl J Med,2002(46):1954-1962. [12]Hollander J, Fiebig R, Gore M, Bejma J, Ookawara T, Ohno H, Ji LL. Superoxide dismutase gene expression in skeletal muscle: fifiber-specifific adaptation to endurance training. Am J Physiol 1999; 277: R856–R862. [13] Abraham P, Saumet JL, Chevalier JM. External iliac artery endofifibrosis in athletes[J].Sports Med,1997(24):221-226. [14]Guidelines Sub-Committee.1993 Guideline for the management of mild hypertension: memorandum from World Health Organization/International Society of Hypertension meeting[J].J Hypertens,1993(11):905-911. [15]Tsai H-H, Lin C-P, Lin Y-H, Hsu C-C,Wang J-S. High-intensity interval training enhances mobilization/functionality of endothelial progenitor cells and depressed shedding of vascular endothelial cells undergoing hypoxia. Eur J Appl Physiol[J].2016,116(11-12):2375-88. [16]Sonnenschein K, Horváth T, Mueller M, et al. Exercise training improves in vivo endothelial repair capacity of early endothelial progenitor cells in subjects with metabolic syndrome[J].Eur J Cardiovasc Prev Rehabil,2011,18(3):406-14. [17]Sandri M, Viehmann M, Adams V, et al. Chronic heart failure and aging– effects of exercise training on endothelial function and mechanisms of endothelial regeneration: results from the Leipzig Exercise Intervention in Chronic heart failure and Aging (LEICA) study[J].Eur J Prev Cardiol,2016,23(4):349-58. [18]Sen S, Islam A, Witkowski S. Changes in function and gene expression in endothelial progenitor cells (EPCs) leads to improvement in flow mediated dilatation and serum markers in patients with prediabetes following aerobic exercise[M]Paper presented at:DIABETES,2014. [19]Hoellriegel R, Beck E, Woitek F, et al. Regular physical exercise training partially corrects metabolic alterations and improves peripheral endothelial function in pre-diabetic, adipose patients with coronary artery disease[M].Paper presented at: American Journal of Respiratory and Critical Care Medicine,2011. [20]Hashida R, Kawaguchi T, Bekki M, et al. Aerobic vs. resistance exercise in nonalcoholic fatty liver disease: a systematic review[J].J Hepatol,2017,66(1):142-52. [21]Ross MD,Wekesa AL,Phelan JP, Harrison M. Resistance exercise increases endothelial progenitor cells and angiogenic factors[J].Med Sci Sports Exerc,2014,46(1):16-23. [22]Ribeiro F, Ribeiro IP, Gonçalves AC, et al. Effects of resistance exercise on endothelial progenitor cell mobilization in women[J].Sci Rep,2017,7(1):17880. [23]Waclawovsky G, Umpierre D, Figueira FR, et al. Exercise on progenitor cells in healthy subjects and patients with type 1 diabetes[J].Med Sci Sports Exerc,2015(48):190-9. [24]Edwin Chang, Josemaria Paterno, et al.Exercise Induces Stromal Cell–Derived Factor- 1α–Mediated Release of Endothelial Progenitor Cells with Increased Vasculogenic Function[J].American Society of Plastic Surgeons,2015(05):340-349. [25]M.J. Pearson, N.A. Smart.Effect of exercise training on endothelial function in heart failure patients: A systematic review meta-analysis[J].International Journal of Cardiology,2017(231):234-243. [26]Turgeon J,Haddad P,Dussault S,Groleau J,Maingrette F, Perez G, et al.Protection against vascular aging in Nox2-deficient mice: Impact on endothelial progenitor cells and reparative neovascularization[J].Atherosclerosis,2012(223):122-129. [27]Chen DD, Dong YG, Yuan H, Chen AF. Endothelin 1 activation of endothelin A receptor/NADPH oxidase pathway and diminished antioxidants critically contribute to endothelial progenitor cell reduction and dysfunction in salt-sensitive hypertension[J].Hypertension,2012(59):1037-1043. [28]Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease[J].Circ Res,2001(89):E1-E7. [29]Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk[J].N Engl J Med,2003(348):593-600. [30]Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, et al. Circulating endothelial progenitor cells and cardiovascular outcomes[J].N Engl J Med,2005(353):999-1007. [31]Matsumoto Y, Adams V, Walther C, Kleinecke C, Brugger P, Linke A, et al. Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair[J].Eur Heart J,2009(30):346-355. [32]Imanishi T, Kobayashi K, Hano T, Nishio I. Effect of estrogen on differentiation and senescence in endothelial progenitor cells derived from bone marrow in spontaneously hypertensive rats[J].Hypertens Res,2005(28):763-772. [33]Imanishi T,Moriwaki C,Hano T, Nishio I. Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension[J].J Hypertens,2005(23):1831-1837. [34]Pirro M, Schillaci G, Menecali C, Bagaglia F, Paltriccia R, Vaudo G, et al. Reduced number of circulating endothelial progenitors and HOXA9 expression in CD34þ cells of hypertensive patients[J].J Hypertens,2007(25):2093-2099. [35]Van Zonneveld AJ, Rabelink TJ. Endothelial progenitor cells: biology and therapeutic potential in hypertension[J].Curr Opin Nephrol Hypertens,2006(2):167-172. [36]Hagberg JM, Park JJ, Brown MD. The role of exercise training in the treatment of hypertension: an update[J].Sports Med,2000(30):193-206. [19,20].Amaral SL, Zorn TM, Michelini LC. Exercise training normalizes wall-tolumen ratio of the gracilis muscle arterioles and reduces pressure in spontaneously hypertensive rats[J].J Hypertens,2000(18):1563-1572. [37]Melo RP, Martinho E Jr, Michelini LC. Training-induced, pressurelowering effect in SHR wide effects on circulatory profile of exercised and nonexercised muscles. Hypertension 2003; 42:851–857. [38]Fernandes T, Magalha˜es FC, Redondo FRR, Phillips MI, Oliveira EM. Exercise training prevents the microvascular rarefaction in hypertension balancing angiogenic and apoptotic factors: role of microRNAs-16, -21 and -126[J].Hypertension,2012(59):513-520. [39]Loomans CJ, Dao HH, Van Zommeveld AJ, Rabelink TJ. Is endothelial progenitor cell dysfunction involved in altered angiogenic processes in patients with hypertension? [J].Curr Hypertens Rep,2004(6):51-54. [40]Laufs U, Werner N, Link A, Endres M, Wassmann S, Jurgens K, et al. Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis[J].Circulation,2004(109):220-226. [41]Steiner S, Niessner A, Ziegler S, Richter B, Seidinger D, Pleiner J, et al. Endurance training increases the number of endothelial progenitor cells in patients with cardiovascular risk and coronary artery disease[J].Atherosclerosis,2005(181):305-310. [42]Sandri M,Adams V,Gielen S,Linke A,Lenk K, Kra¨nkel N, et al. Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemia syndromes: results of 3 randomized studies[J].Circulation,2005(111):3391-3399. [43]Wahl P, Block W, Shmidt A. Exercise has a positive effect on endothelial progenitor cells, which could be necessary for vascular adaptation processes[J].Int J Sports Med,2007(28):374-380.


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