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一例误诊为脑梗死的抗Ig1on5抗体阳性的自身免疫性脑炎

姚洪宇, 卓文燕, 刘礼斌

摘要

目的：总结1例易误诊为脑梗死的抗Ig1on5抗体阳性的自身免疫性脑炎的临床诊治经验。方法：对患者的临床资料进行回顾与分析。结果：患者中年男性，以视力下降起病，逐渐进展为“三偏征”样临床表现，多次按照脑梗死治疗，效果不佳。我院颅脑MR DWI相脑内多发稍高信号病灶，完善脑脊液检测抗Ig1on5抗体阳性，经冲击治疗疗效欠佳。后自动出院，2月后随访患者症状无改善，且出现严重的失眠，半年后随访患者已故。结论：对于亚急性病程、临床主征为“三偏征”、MR DWI显示颅内多发高信号病变患者应排查抗Ig1on5抗体阳性自身免疫性脑炎，早发现早治疗。

关键词

抗Ig1on5抗体阳性；自身免疫性脑炎；脑梗死

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参考

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