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皮肤和肠道微生物菌群与白癜风相关性的研究进展

阿丽 曼·, 李治 建*, 吐尔 逊·, 热孜 万古, 居来 提·

摘要

白病(白癜风)是由于体内黏液质的异常变化沉淀在皮肤和黏膜,使排泄力和改造力功能发生紊乱而影响皮肤的着色能力,皮肤出现白斑为主要的物质失调类疾病。白癜风的发病机制复杂,涉及遗传、免疫和环境因素,其中包括微生物菌群,皮肤和肠道微生物菌群失调可能是白癜风发展的诱因之一。维吾尔医学中体液成熟剂可能通过调节肠道微生物菌群生态环境而影响白癜风的治疗效果。本文主要对国内外研究白癜风患者皮肤和肠道微生物菌群的组成及其功能特征进行综述,为研究白癜风的发病机制及诊疗思路提供参考依据。

关键词

白癜风;微生物菌群;体液成熟剂;WNT通路

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参考

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通讯作者:李治建(1982-),男,汉族,新疆乌鲁木齐市人,博士,新疆维吾尔自治区维吾尔医医院,博士研究生导师/硕士研究生导师。吐尔逊·乌甫尔(1964-),男,维吾尔族,新疆乌鲁木齐市人,硕士,新疆维吾尔自治区维吾尔医医院,主任医师,硕士研究生导师。热孜万古丽·乌买尔(1968-),女,维吾尔族,新疆乌鲁木齐市人,硕士,新疆维吾尔自治区维吾尔医医院,主任医师。居来提·阿不都瓦衣提(1984-),男,维吾尔族,新疆乌鲁木齐市人,硕士,新疆维吾尔自治区维吾尔医医院,主任医师。


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