如何磷危不惧,摆脱瘙痒?
摘要
(11.7%-15.1%),且是进行性、不可逆的,终末期其替代治疗方式包括血液透析、腹膜透析和肾移植 [1]。据报道,2030 年
全球预计需要进行肾脏替代治疗的患者人数将达到 500 多万,而未来需进行血液透析治疗的患者更会逐年增加 [2]。磷,作
为一种在食物中广泛存在的营养物质,对于人体健康至关重要。然而,对于维持性血液透析患者而言,磷却可能成为一大
健康威胁。高磷血症是维持性血液透析 (maintenance hemodialysis,MHD)患者常见的并发症,可造成矿物质和骨代谢紊乱、
继发性甲状旁腺功能亢进及血管钙化的发生。目前全球透析预后和实践模式研究(the come and practice patterns dialysis out
study,DOPPS)显示,MHD 患者的高磷血症管理情况并不乐观,世界各国透析患者高磷血症发生率均较高,美国 MHD
患者高磷血症(血磷 >1.78 mmol/L)的发生率为 52%,而我国血磷控制情况更不理想,高磷血症的发生率为 72.1%,血磷
平均值为 1.94mmol / L,是所有参加 DOPPS 研究国家中最高的 [3-5]。
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