血压与糖尿病视网膜病变的关联:双样本孟德尔随机化研究
摘要
纯性 DR 的因果关系。方法 进行单变量和多变量孟德尔随机化分析。逆方差加权是用于分析因果关系的主要方法,并伴有
几种敏感性 MR 分析。结果 遗传预测的原发性高血压、更高的收缩压与 DR 风险增加相关。原发性高血压,MR 分析仅支
持原发性高血压和单纯性 DR 高风险有关。结论 研究表明,原发性高血压、过高的收缩压和舒张压可能会增加 DR 的风险。
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