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心力衰竭患者利尿剂抵抗的机制及治疗进展

袁 巧萌, 亢庆 军*, 杨 静, 杨 霞, 吴 秋菊

摘要

利尿剂是心力衰竭患者水钠潴留时的首选治疗。利尿剂抵抗表现为对利尿剂的反应减低甚至完全失效,是治疗过
程中常见的一大临床难题,常常导致住院期间患者的病情恶化,同时导致患者的住院时间延长、病死率和再住院率增加。
利尿剂抵抗是当前重要的研究内容,本文将从利尿剂抵抗的机制、治疗方法及进展等方面进行综述,为临床利尿剂的治疗
提供帮助。

关键词

利尿剂抵抗;心力衰竭;发病机制;治疗方法;研究进展;综述

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