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基于 MRI 平扫影像组学辅助卵巢常见良性上皮肿瘤鉴别诊断

孟 爽, 王 欣欣, 陈 璐军, 沈 鹏翔, 王向 明*

摘要

目的:卵巢良性肿瘤中以上皮性浆液性肿瘤及黏液性肿瘤居多,采用影像组学技术探讨 T1WI 平扫序列在分类卵
巢良性浆液性(BST)与黏液性(BMT)囊腺瘤中的鉴别价值。方法 : 回顾性分析 2012 年 5 月至 2023 年 12 月义乌市中心
医院 175 例术后常规病理检查确诊为 BST 或 BMT, 并于术前行盆腔磁共振平扫检查。按7:3随机分成 121 例训练组和 54
例验证组,利用 T1WI 平扫影像提取影像组学特征并进行 LASSO 算法,构建影像组学标签、得到影像组学分数模型,采用
受试者工作曲线 (ROC) 和校正曲线对不同模型的预测性能进行评价。结果:在影像组学分析中,提取 396 个影像组学纹理
特征,降维提取 9 个最优影像组学参数创建影像组学标签。训练组中 T1WI 影像组学模型中鉴别良性浆液性与黏液性囊腺
瘤的平均 AUC、特异度、灵敏度分别为 0.768 (P<0.05)、74.6%、66.7%;在验证组中,AUC、特异度、灵敏度分别为 0.731
(P<0.05)、80.0%、75%。结论:基于术前 MRI 平扫检查建立的放射组学标签预测模型在卵巢良性浆液性肿瘤和黏液性肿
瘤分类中取得了良好的预测性能。

关键词

卵巢肿瘤;囊腺瘤;磁共振成像;影像组学;分类

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