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重复经颅磁刺激治疗偏头痛疗效观察

张 明之, 陈 莉, 邢晓 娜*

摘要

目的 观察重复经颅磁刺激(rTMS)治疗偏头痛的疗效和安全性。方法 随机纳入 rTMS 治疗组及假刺激组各 51 人,
rTMS 组给予重复经颅磁刺激治疗,隔日 1 次,15 次为一疗程,假刺激组使用伪线圈,不产生磁场效应。记录治疗前后头
痛持续时间,头痛发作频率、视觉模拟评分量表评分、整体印象量表评分等。结果 rTMS 组治疗后头痛发作频率、VAS 评分、
临床症状及生活质量明显改善(P <0.05),且无明显不良反应。结论 rTMS 是治疗偏头痛有效且安全的治疗方法。

关键词

重复经颅磁刺激;偏头痛;疗效;安全性

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参考

[1] 中华医学会神经病学分会 , 中华医学会神经病学分

会头痛协作组 . 中国偏头痛诊断与治疗指南(中华医学会神

经病学分会第一版). 中华神经科杂志 ,2023,56(6):591-613

[2] 陈月秋 , 石静萍 . 经颅磁刺激在偏头痛的预防及治疗

方面的应用 . 中国疼痛医学杂志 .2018,24(6):451-455

[3]Headache Classification Committee of the International

Headache Society (IHS) The International Classification of

Headache Disorders, 3rd edition. Cephalalgia. 2018 Jan;38(1):1-

211. doi: 10.1177/0333102417738202. PMID: 29368949. 2018;

38: 1-211.

[4]Andreou AP, Edvinsson L. Mechanisms of migraine

as a chronic evolutive condition. J Headache Pain. 2019 Dec

23;20(1):117. doi: 10.1186/s10194-019-1066-0. PMID:

31870279; PMCID: PMC6929435.

[5]Kissoon NR, Cutrer FM. Aura and Other Neurologic

Dysfunction in or with Migraine[J]. Headache, 2017,57:1179-

1194.

[6]Ayata C, Lauritzen M. Spreading Depression, Spreading

Depolarizations, and the Cerebral Vasculature[J].Physiol Rev,

2015, 95:953-993.

[7] 杨梦丽 唐闻晶 于生元 . 皮层扩布性抑制与偏头痛的

相关研究进展 . 中国疼痛医学杂志 , 2019, 25 (8):614-623

[8]Levy D,Labastida-Ramirez A,MaassenVanDenBrink

A. Current understanding of meningeal and cerebral vascular

function underlying migraine headache[J]. Cephalalgia,2019,

39(13):1606-1622.

[9]Barr MS, Farzan F, Davis KD, et al . Measuring GABAergic inhibitory activity with TMS-EEG and its potential

clinical application for chronic pain. Journal of neuroimmune

pharmacology: the official journal of the Society on NeuroImmune

Pharmacology, 2013,8(3):5

[10]Andreou AP,Holland PR,Akerman S,et al.

Transcranial magnetic stimulation and potential cortical and

trigeminothalamic mechanisms in migraine[J]. Brain,2016,

139(7):2002-2014.

[11] 郭雨 , 李安然 , 姚刚 . 经颅磁刺激治疗慢性头痛的

研究进展 . 中风与神经疾病杂志 , 2020, 37(6): 565-567

[12]Misra UK,Kalita J,Bhoi SK. High-rate repetitive

transcranial magnetic stimulation in migraine prophylaxis: a

randomized,placebo-controlled study. J Neurol,2013,

260(11):2793-2801.

[13]Kumar S,Singh S,Kumar N,et al. The effects

of repetitive transcranial magnetic stimulation at dorsolateral

prefrontal cortex in the treatment of migraine comorbid with

depression: A retrospective open study[J]. Clin Psychopharmacol

Neurosci,2018,16(1):62-66.

[14]Knotkova H, Hamani C, Sivanesan E, et al .

Neuromodulation for chronic pain[J]. Lancet, 2021, 397

(10289):2111-2124.

[15] 马奕然 , 庞淼一 , 王怡然等 . 运动皮质刺激治疗神经

病理性疼痛研究进展 . 中国疼痛医学杂志 , 2023, 29(5):324-

331

[16]Lefaucheur J, Nguyen J. A practical algorithm for using

rTMS to treat patients with chronic pain[J]. Neurophysiol Clin,

2019, 49(4):301-307.

[17]Stilling JM,Monchi O,Amoozegar F,et al.

Transcranial magnetic and direct current stimulation (TMS/tDCS)

for the treatment of headache:A systematic review[J]. Headache,

2019,59(3):339-357.

[18]Zhong J, Lan W, Feng Y, Yu L, Xiao R, Shen Y, Zou Z,

Hou X. Efficacy of repetitive transcranial magnetic stimulation

on chronic migraine: A meta-analysis. Front Neurol. 2022

Nov 24;13:1050090. doi: 10.3389/fneur.2022.1050090. PMID:

36504667; PMCID: PMC9730425.


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