开放期刊系统

干细胞在心血管疾病的研究现状

王 丹, 杨 萌甜, 何 端, 王 星玉, 潘军 强*

摘要

心血管疾病是当前全球死亡的主要原因,在当前治疗中,重点内容涉及介入治疗、基础药物治疗、外科治疗及心
脏移植 , 然而药物治疗和介入治疗、外科治疗等治疗 , 对心脏纤维化、心室重构、心肌病无明显效果。心脏移植则是终末期
心力衰竭的有效解决方案,但供体少,花费大,有能力开展心脏移植的医疗机构少。近年来 , 干细胞治疗已成为一个非常
有发展前途科学研究课题。干细胞在诱导和分化作用下,能以定向分化的方式产生收缩功能心肌细胞、内皮细胞、平滑肌
细胞等,使其能直接进入缺血坏死心肌区域 , 促进心肌和心脑血管再生反应,不断提升心功能,所以干细胞将成为生物医
学研究的重点方向 [1]。本文就干细胞在心血管疾病的应用现状作一综述 , 同时开展心血管机制的研究、诊断工作,为治疗
方案的规划提供方向。

关键词

干细胞;冠状动脉粥样硬化性心脏病;心肌梗死;心力衰竭

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参考

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