一种建立股骨骨折镁合金髓内针固定模型的方法研究
摘要
右侧股骨中段制作 1/2 的骨折线，剩余部分人为离断，然后，由股骨远端髁间窝将镁合金髓内针（以下简称：
镁针）从远端打入到股骨近端，制成骨折内固定模型。模型制备后，观察大鼠肢体活动状况、X 线以确定骨折
线及髓内针的位置，8 周后处死所有大鼠，行大体解剖肝、肾组织行 HE 染色后观察其镜下表现。结果 8 周后
30 只 SD 大鼠均存活，患肢未发生畸形、感染现象，X 线下均显示骨折固定良好，植入一侧的股骨相较未植入
一侧明显增粗，骨量增多。肝肾重要脏器组织形态结构未见异常。结论 利用镁合金髓内针固定股骨骨折是一
种稳定可靠、可以在基础研究中推广使用的建模方法。
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