开放期刊系统

雄激素在妇女更年期对心血管衰老的影响

宋 丽媛

摘要

更年期是女性的关键生命阶段,虽然雌激素水平的下降长期以来一直被认为是更年期妇女心血管衰老的主要原因,
但雄激素的作用近年来越来越受到关注。本综述旨在全面了解更年期妇女体内雄激素水平对心血管衰老的影响。通过文献
检索,探讨更年期、雄激素和心血管衰老之间的关系。该综述探讨了雄激素雄激素对心血管系统的作用机制,雄激素替代
疗法 (ART)对更年期妇女心血管风险标志物和事件的影响。本综述全面了解了更年期雄激素对心血管衰老的影响,并为
管理更年期妇女的心血管衰老提供了见解。

关键词

激素替代疗法、雄激素、心血管衰老、更年期

全文:

PDF

参考

[1] InS WSGOO, WHO. Research on the menopause in

the 1990s. Report of a WHO Scientific Group: Research on the

menopause in the 1990s ;1996.

[2] Peacock K, Ketvertis KM. Menopause. StatPearls.

Treasure Island (FL) ineligible companies. Disclosure:

Kari Ketvertis declares no relevant financial relationships with

ineligible companies.: StatPearls Publishing Copyright © 2023,

StatPearls Publishing LLC.;2023.

[3] Ryczkowska K, Adach W, Janikowski K , et al.Menopause

and women’s cardiovascular health: is it really an obvious

relationship? Archives of medical science : AMS. 2023;19

(2):458-66.

[4] Chistiakov DA, Myasoedova VA, Melnichenko AA, et al.

Role of androgens in cardiovascular pathology. Vasc Health Risk

Manag. 2018;14:283–290.

[5] Sandoo A, van Zanten JJ, Metsios GS, et al. The

endothelium and its role in regulating vascular tone. Open

Cardiovasc Med J. 2010;4:302–312.

[6] Liu PY, Death AK, Handelsman DJ. Androgens and

cardiovascular disease. Endocr Rev. 2003;24(3):313–340.

[7] Pace S, Werz O. Impact of androgens on inflammationrelated lipid mediator biosynthesis in innate immune cells. Front

Immunol. 2020;11:1356.

[8] Ayaz O, Howlett SE. Testosterone modulates cardiac

contraction and calcium homeostasis: cellular and molecular

mechanisms. Biol Sex Differ. 2015;6:9.

[9] Villa P, Amar ID, Shachor M, et al. Cardiovascular risk/

benefit profile of MHT. Medicina (Kaunas) 2019;55:571.

[10] Lucà F, Abrignani MG, Parrini I, et al. Update on

management of cardiovascular diseases in women. J Clin Med.

2022;11:1176.

[11] Liu Y, Ding J, Bush TL, et al. Relative androgen excess

and increased cardiovascular risk after menopause: a hypothesized

relation. Am J Epidemiol. 2001;154: 489–494.

[12] Pérez-López FR, Larrad-Mur L, Kallen A, et al.

Gender differences in cardiovascular disease: hormonal and

biochemical influences. Reprod Sci. 2010;17:511–531.

[13]. Gallucci G, Tartarone A, Lerose R, et al. Cardiovascular

risk of smoking and benefits of smoking cessation. J Thorac Dis.

2020;12:3866–3876.

[14] Dimsdale JE. Psychological stress and cardiovascular

disease. J Am Coll Cardiol. 2008;51(13):1237-46.


(23 摘要 Views, 45 PDF Downloads)

Refbacks

  • 当前没有refback。