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XI 因子抑制剂在心房颤动治疗中的研究现状

李 文涛, 金雄 杰*

摘要

心房颤动是临床上最常见的心律失常之一,其可导致严重的血栓栓塞并发症,而预防房颤患者血栓栓塞事件的关键策
略是抗凝治疗。抗凝治疗是预防房颤患者血栓栓塞事件的关键策略。近年来,作为凝血级联反应重要组成部分的XI因
子成为抗凝治疗新靶点,XI因子抑制剂能抑制XI因子活性以阻断凝血过程,在抗凝效果和安全性方面有着独特的特点。
本文旨在讨论XI因子抑制剂在房颤治疗中的临床研究进展,分析其作用机制、临床疗效、安全性,比较其与传统抗凝
药物,探讨未来研究方向和临床应用前景,为房颤抗凝治疗提供更全面的理论依据和实践指导。

关键词

XI因子抑制剂;心房颤动;抗凝治疗;出血风险;

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参考

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