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耐碳青霉烯类肠杆菌目的研究进展

王 晨陈, 金 春梅

摘要

耐碳青霉烯类肠杆菌目(Carbapenem-resistantEnterobacteriaceae,CRE)的感染已成为了全球范围内公共卫生关注的焦点之一。CRE不仅对碳青霉烯类抗菌药物表现出耐药性,而且对其他抗菌药物也表现出耐药性,因此治疗选择受到了极大限制,进而导致医疗花费的增加以及患者死亡率的上升。尽管目前对于CRE的研究已经取得了一定的进展,但其耐药性极其复杂和持续变化,其中产碳青霉烯酶为CRE最重要的耐药机制。本文对CRE产碳青霉烯酶的研究进展进行主要综述,从而减少CRE感染的发生和传播。

关键词

耐碳青霉烯类肠杆菌目;碳青霉烯酶;流行特征

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参考

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作者简介:王晨陈,生于 1998 年,女,硕士。

基金项目:吉林省科技发展计划项目 YDZJ202501ZYTS224。


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