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托珠单抗联合激素治疗重型 COVID-19 的机制及研究进展

王 丹, 朴 红梅

摘要

新型冠状病毒感染引发的重症病例常伴随过度炎症反应和细胞因子风暴,导致多器官功能衰竭。托珠单抗作为白介素-6受体拮抗剂,与糖皮质激素联合应用,通过协同抑制炎症反应和调节免疫应答,成为重症及危重症新冠肺炎的重要治疗策略。本文综述了托珠单抗联合糖皮质激素的作用机制、临床研究进展及安全性,以期为优化治疗方案提供理论依据。

关键词

托珠单抗;糖皮质激素;细胞因子风暴;新型冠状病毒

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参考

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