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维持性血液透析患者认知障碍的影响因素及研究进展

王 璐, 守 丹, 高 祖梅

摘要

随着全球老龄化加剧,慢性肾脏病(Chronic Kidney Disease,CKD)尤其是维持性血液透析(Maintenance Hemodialysis,MHD)患者中认知障碍的高发性及其对患者生活质量和预后的不利影响引起了广泛关注。本综述阐述了MHD患者认知障碍的流行病学特点、病理生理机制、筛查与评估工具以及干预与治疗策略。重点介绍了心血管风险因素管理、透析技术改进如透析冷却技术以及肾移植对认知功能的保护作用。未来研究应聚焦于认知障碍的机制研究、新型透析方法的开发及筛查工具的优化,以改善患者的预后和生活质量。

关键词

维持性血液透析;终末期肾病;认知障碍;筛查工具

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参考

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Fund programs:This project has practical values and is supported by the Doctoral Starting up Foundation of The First Affiliated Hospital

of Yangtze University(2022DIF04).


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