开放期刊系统

重新认识微生物在生命早期的意义

李 玲, 段 淼, 胡 联富, 贺 云飞

摘要

微生物的组成及其代谢物的稳定对于人体的健康至关重要,它们共同协作组合的微生物组与先天宿主细胞通过复杂地相互作用共同发展,其中特定微生物的组分及其丰度和宿主的年龄以及后天环境的暴露是有所不同的。随着微生物学和基因测序技术的发展,进一步揭示了微生物对健康、疾病发生发展方面的影响。新生儿肠道微生物结构及组成变化较大,并且各器官功能未发育成熟,极易受外环境影响从而导致疾病的发生,甚至死亡,因此,借助于现阶段肠道微生物的研究,重新解读可以扩展对新生儿期疾病的认识,为临床诊断及治疗开阔视野,具有深远的意义。

关键词

微生物,新生儿,肠道菌群

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参考

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